Where are we with the management of hypertension? From science to clinical practice

Csaba Farsang, Lisa Naditch-Brule, Angelo Avogaro, Jan Östergren, Paolo Verdecchia, Aldo Maggioni, Philippe van de Borne, Robert Lins, Alexandre Roca-Cusachs

Research output: Review article

14 Citations (Scopus)


The management of elevated blood pressure in patients at high cardiovascular risk is still a subject of debate. The authors review current international guidelines and results of large clinical trials and recent meta-analyses to discuss the different approaches in patients at high risk for cardiovascular events. The different treatment options are considered in view of the modern approach and of the different classes of drugs (diuretics, angiotensin-converting enzyme inhibitors, calcium channel blockers, β-blockers, and angiotensin II receptor blockers) currently in use. A case report is presented as an illustration of the difficulties related to the management of high blood pressure in patients at increased risk. The benefits of the use of 2 medications that include an inhibitor of the renin-angiotensin-aldosterone system and a calcium channel blocker or a diuretic are discussed. Choosing the proper drugs and correct doses are important considerations for the long-term management of hypertension.

Original languageEnglish
Pages (from-to)66-73
Number of pages8
JournalJournal of Clinical Hypertension
Issue number2
Publication statusPublished - febr. 25 2009


ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Cardiology and Cardiovascular Medicine

Cite this

Farsang, C., Naditch-Brule, L., Avogaro, A., Östergren, J., Verdecchia, P., Maggioni, A., van de Borne, P., Lins, R., & Roca-Cusachs, A. (2009). Where are we with the management of hypertension? From science to clinical practice. Journal of Clinical Hypertension, 11(2), 66-73. https://doi.org/10.1111/j.1751-7176.2008.00066.x