Wasting disease and tetany following neonatal pinealectomy

G. Csaba, I. Rados, E. Wohlmuth

Research output: Article

6 Citations (Scopus)


The physiological parameters of development and the microscopic appearance of thymus, thyroid, parathyroids, ultimobranchial body and bursa of Fabricius have been studied in chicks (Gallus domesticus) after pinealectomy performed on the first day after hatching. Arrested development and excessive shedding of the plumage were found as a sign of wasting disease resulting from atrophy of the thymus and bursa. Tetany ensued in 50% of the chicks and proved fatal to 35% in the absence of any abnormality of the parathyroids. The possible mechanism of the phenomenon and the role of the pineal body in the regulation of the glands of entodermal origin are discussed.

Original languageEnglish
Pages (from-to)231-240
Number of pages10
JournalActa Medica Academiae Scientiarum Hungaricae
Issue number3-4
Publication statusPublished - 1972


ASJC Scopus subject areas

  • Medicine(all)

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