Validation of arteriograph - A new oscillometric device to measure arterial stiffness in patients on maintenance hemodialysis

János Nemcsik, József Egresits, Taha El Hadj Othmane, Bertalan Csaba Fekete, Erzsébet Fodor, Tamás Szabó, Z. Járai, Csaba Jekkel, István Kiss, A. Tislér

Research output: Article

23 Citations (Scopus)

Abstract

Background: Measuring arterial stiffness (augmentation index (AI), aortic pulse wave velocity (PWV)) in hemodialysis (HD) patients has prognostic significance. To assess its validity, the new oscillometric Arteriograph device (AIA, PWVA) was compared to the validated PulsePen tonometer (AIP, PWVP). Methods: AI and PWV were measured in 98 patients with both devices before HD. Validity was evaluated by Pearson's correlation, Bland-Altman analysis, and by assessing the prognostic value of AI and PWV to predict cardiovascular (CV) mortality over 29 months. Results: Correlation between AIP and AIA was significant (R = 0.527, p <0.001). The mean difference of AI values obtained by the two devices was -20.6%, and 30% of the paired AI differences fall outside the ±1 SD boundary of the mean between-device difference. There was no significant correlation between the PWVP and PWVA readings (R = 0.173, p = 0.097). The average difference of PWV values by the two devices was -1.2 m/s, and 20.6% of the paired PWV differences fall outside the ±1 SD boundary. In survival analyses, only PWVP but not PWVA was significantly related to CV mortality. Conclusion: Lack of correlation between PWVP and PWVA and lack of prognostic significance of PWVA suggest limited validity of Arteriograph to determine PWV in patients on HD.

Original languageEnglish
Pages (from-to)223-229
Number of pages7
JournalKidney and Blood Pressure Research
Volume32
Issue number3
DOIs
Publication statusPublished - aug. 2009

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Pulse Wave Analysis
Vascular Stiffness
Renal Dialysis
Maintenance
Equipment and Supplies
Mortality
Survival Analysis
Reading

ASJC Scopus subject areas

  • Nephrology
  • Cardiology and Cardiovascular Medicine

Cite this

Validation of arteriograph - A new oscillometric device to measure arterial stiffness in patients on maintenance hemodialysis. / Nemcsik, János; Egresits, József; El Hadj Othmane, Taha; Fekete, Bertalan Csaba; Fodor, Erzsébet; Szabó, Tamás; Járai, Z.; Jekkel, Csaba; Kiss, István; Tislér, A.

In: Kidney and Blood Pressure Research, Vol. 32, No. 3, 08.2009, p. 223-229.

Research output: Article

Nemcsik, János ; Egresits, József ; El Hadj Othmane, Taha ; Fekete, Bertalan Csaba ; Fodor, Erzsébet ; Szabó, Tamás ; Járai, Z. ; Jekkel, Csaba ; Kiss, István ; Tislér, A. / Validation of arteriograph - A new oscillometric device to measure arterial stiffness in patients on maintenance hemodialysis. In: Kidney and Blood Pressure Research. 2009 ; Vol. 32, No. 3. pp. 223-229.
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abstract = "Background: Measuring arterial stiffness (augmentation index (AI), aortic pulse wave velocity (PWV)) in hemodialysis (HD) patients has prognostic significance. To assess its validity, the new oscillometric Arteriograph device (AIA, PWVA) was compared to the validated PulsePen tonometer (AIP, PWVP). Methods: AI and PWV were measured in 98 patients with both devices before HD. Validity was evaluated by Pearson's correlation, Bland-Altman analysis, and by assessing the prognostic value of AI and PWV to predict cardiovascular (CV) mortality over 29 months. Results: Correlation between AIP and AIA was significant (R = 0.527, p <0.001). The mean difference of AI values obtained by the two devices was -20.6{\%}, and 30{\%} of the paired AI differences fall outside the ±1 SD boundary of the mean between-device difference. There was no significant correlation between the PWVP and PWVA readings (R = 0.173, p = 0.097). The average difference of PWV values by the two devices was -1.2 m/s, and 20.6{\%} of the paired PWV differences fall outside the ±1 SD boundary. In survival analyses, only PWVP but not PWVA was significantly related to CV mortality. Conclusion: Lack of correlation between PWVP and PWVA and lack of prognostic significance of PWVA suggest limited validity of Arteriograph to determine PWV in patients on HD.",
keywords = "Arterial stiffness, Arteriograph, validation, Augmentation index, End-stage renal failure, HD patients, Maintenance hemodialysis, Pulse wave velocity, PulsePen tonometer",
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T1 - Validation of arteriograph - A new oscillometric device to measure arterial stiffness in patients on maintenance hemodialysis

AU - Nemcsik, János

AU - Egresits, József

AU - El Hadj Othmane, Taha

AU - Fekete, Bertalan Csaba

AU - Fodor, Erzsébet

AU - Szabó, Tamás

AU - Járai, Z.

AU - Jekkel, Csaba

AU - Kiss, István

AU - Tislér, A.

PY - 2009/8

Y1 - 2009/8

N2 - Background: Measuring arterial stiffness (augmentation index (AI), aortic pulse wave velocity (PWV)) in hemodialysis (HD) patients has prognostic significance. To assess its validity, the new oscillometric Arteriograph device (AIA, PWVA) was compared to the validated PulsePen tonometer (AIP, PWVP). Methods: AI and PWV were measured in 98 patients with both devices before HD. Validity was evaluated by Pearson's correlation, Bland-Altman analysis, and by assessing the prognostic value of AI and PWV to predict cardiovascular (CV) mortality over 29 months. Results: Correlation between AIP and AIA was significant (R = 0.527, p <0.001). The mean difference of AI values obtained by the two devices was -20.6%, and 30% of the paired AI differences fall outside the ±1 SD boundary of the mean between-device difference. There was no significant correlation between the PWVP and PWVA readings (R = 0.173, p = 0.097). The average difference of PWV values by the two devices was -1.2 m/s, and 20.6% of the paired PWV differences fall outside the ±1 SD boundary. In survival analyses, only PWVP but not PWVA was significantly related to CV mortality. Conclusion: Lack of correlation between PWVP and PWVA and lack of prognostic significance of PWVA suggest limited validity of Arteriograph to determine PWV in patients on HD.

AB - Background: Measuring arterial stiffness (augmentation index (AI), aortic pulse wave velocity (PWV)) in hemodialysis (HD) patients has prognostic significance. To assess its validity, the new oscillometric Arteriograph device (AIA, PWVA) was compared to the validated PulsePen tonometer (AIP, PWVP). Methods: AI and PWV were measured in 98 patients with both devices before HD. Validity was evaluated by Pearson's correlation, Bland-Altman analysis, and by assessing the prognostic value of AI and PWV to predict cardiovascular (CV) mortality over 29 months. Results: Correlation between AIP and AIA was significant (R = 0.527, p <0.001). The mean difference of AI values obtained by the two devices was -20.6%, and 30% of the paired AI differences fall outside the ±1 SD boundary of the mean between-device difference. There was no significant correlation between the PWVP and PWVA readings (R = 0.173, p = 0.097). The average difference of PWV values by the two devices was -1.2 m/s, and 20.6% of the paired PWV differences fall outside the ±1 SD boundary. In survival analyses, only PWVP but not PWVA was significantly related to CV mortality. Conclusion: Lack of correlation between PWVP and PWVA and lack of prognostic significance of PWVA suggest limited validity of Arteriograph to determine PWV in patients on HD.

KW - Arterial stiffness

KW - Arteriograph, validation

KW - Augmentation index

KW - End-stage renal failure, HD patients

KW - Maintenance hemodialysis

KW - Pulse wave velocity

KW - PulsePen tonometer

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