Universality of receptor channel responses

Research output: Review article

13 Citations (Scopus)

Abstract

Rate parameters estimated for neurotransmitter-gated receptor channel opening and receptor desensitization are classified according to their dependence on the temporal resolution of the techniques applied in the measurements. Because allosteric proteins constituting receptor channels impose restrictions on the types of model suitable to describe the dynamic response of channels to neurotransmitters, Markovian, non-linear or fractal dynamic models and their possible extension to receptor channel response in excitable membranes are discussed.

Original languageEnglish
Pages (from-to)642-645
Number of pages4
JournalTrends in Pharmacological Sciences
Volume22
Issue number12
DOIs
Publication statusPublished - dec. 1 2001

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology

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