Az acromegalia kezelése

Judit Dénes, Márta Korbonits, Erika Hubina, Miklós Góth

Research output: Review article

4 Citations (Scopus)

Abstract

Growth hormone (GH) hypersecretion leads to acromegaly which is associated with several co-morbidities and increased mortality. Despite of the typical clinical features and modern diagnostic tools, it often takes years from the onset of the disease until the diagnosis. The aims of the treatment are to reduce or control the tumor growth, inhibit the GH hypersecretion, normalize the insulin-like growth factor-I (IGF-I) levels, treat the co-morbidities and therefore reduce mortality. There are three approaches for therapy: surgery, medical management (dopamine agonist, somatostatin analogues and GH receptor antagonist), and radiotherapy. Efficient therapy of the disease is based on the appropriate multidisciplinary team management.

Translated title of the contributionTreatment of acromegaly
Original languageHungarian
Pages (from-to)1384-1393
Number of pages10
JournalOrvosi hetilap
Volume151
Issue number34
DOIs
Publication statusPublished - aug. 1 2010

Keywords

  • GH receptor antagonist
  • acromegaly
  • dopamine agonist
  • somatostatin analogues
  • therapy

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Dénes, J., Korbonits, M., Hubina, E., & Góth, M. (2010). Az acromegalia kezelése. Orvosi hetilap, 151(34), 1384-1393. https://doi.org/10.1556/OH.2010.28877