It has been shown that optical resolution via supramolecular compound (SMC) formation with O,O′-dibenzoyl-(2R,3R)-tartaric acid (DBTA) can be performed not only by the previously described way (i.e. in hexaneous solution), but also without a solvent, in the melt of the racemate. The resolution of racemic menthol and neomenthol was investigated by preparative and thermoanalytical methods. The resolution in melt is not only simpler and faster, but the efficiency of the resolution has proved to be higher in the case of the menthol. The neomenthol forms no SMC with DBTA in hexaneous solution, but in melt we were able to obtain a SMC and to perform a resolution.
|Number of pages||7|
|Journal||Journal of Thermal Analysis and Calorimetry|
|Publication status||Published - ápr. 13 2004|
ASJC Scopus subject areas
- Condensed Matter Physics
- Physical and Theoretical Chemistry