Magnetic resonance imaging (MRI) is one of those non-invasive proceedings, which allows to measure at the same time the morphologic and functional specificities of the brain, therefore it can help to understand the causes of epilepsy. As far as the authors know, in the literature there is no such study at the present, which would process the cerebral and cerebellar sizes of epileptic dogs based on MR imaging. The aim of the study was to obtain basic datas of the cerebellar volume of different sized dogs and to examine that cerebellar atrophy could be in the background of epilepsy in the case of dogs just like in human patients. Their main question was if it is possible to identify epilepsy in canine patients by using magnetic resonance imaging of cerebellar volumetry? 16 female and 24 male dogs were scanned (n=40), there were 10 entities in every group. The dogs' average age was 5.5. The volumetric evaluation of cerebellum and cerebrum was made by Osiris4 software, based on MR pictures. The four groups were the following: (1) healthy dogs with negative MR, (2) epileptic dogs without MRI findings, (3) epileptic dogs with MRI pathology and (4) dogs affected with cerebral or cerebellar disease but not with epilepsy. 28 cadaver brains volume were also measured with water deplacement method getting baseline datas and to help to select the most appropriate MR sequence and plane for the measurement. Datas were evaluated about cerebral and cerebellar volumetry in different sized, aged and gendered dogs using magnetic resonance imaging method. A detectable reduction was found in cerebellar volumetry in the groups of epileptic dogs, although, this reduction in the volumetric datas was not statistically significant different (p=0.11, p=0.15) in the comparison between the control (negative) and the two epileptic groups. The results of this investigation also demonstrate that the most informative plane is the transversal for canine patients. Recent research may be a background of further studies, which should be carried out on a larger population number completed with pathological examination.
|Translated title of the contribution||The volumetric evaluation of the canine cerebellum by using magnetic resonance imaging|
|Number of pages||10|
|Journal||Magyar Allatorvosok Lapja|
|Publication status||Published - nov. 1 2013|
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