Der rechte Vorhof beim idiopathischen hypereosinophilen Syndrom: Erkenntnisse aus der 3‑D-Speckle-Tracking-Echokardiogaphie-MAGYAR-Path-Studie

A. Nemes, I. Marton, P. Domsik, A. Kalapos, Pósfai, S. Modok, Kormányos, N. Ambrus, Z. Borbényi, T. Forster

Research output: Article

3 Citations (Scopus)


Background: Idiopathic hypereosinophilic syndrome is characterized by a persistent eosinophil blood count of >1.5 × 109 cells/l and organ damage, independent of the primary and secondary causes of eosinophilia. The purpose of the present study was to assess the three-dimensional speckle tracking echocardiography-derived right atrial volumetric and functional properties between hypereosinophilic syndrome patients and matched controls. Methods: A total of 11 patients with idiopathic hypereosinophilic syndrome and 22 age- and gender-matched healthy controls were enrolled in the study. Three-dimensional speckle tracking echocardiography was used for calculation of right atrial volumes, volume-based functional properties, and strain parameters. Results: Significantly increased right atrial maximum (68.7 ± 33.1 ml vs. 40.3 ± 12.1 ml, respectively; p = 0.001) and minimum volumes (48.3 ± 31.0 ml vs. 28.3 ± 9.4 ml, respectively; p = 0.009), as well as right atrial volume before atrial contraction (58.6 ± 27.3 ml vs. 34.5 ± 11.8 ml, respectively; p = 0.001), were found in hypereosinophilic syndrome patients compared with controls. Total and passive right atrial stroke volumes proved to be significantly increased in hypereosinophilic syndrome patients. However, global and mean segmental strain parameters did not differ significantly between the groups. Conclusion: Increased cyclic right atrial volumes and mild alterations in right atrial functional properties could be demonstrated in idiopathic hypereosinophilic syndrome patients.

Translated title of the contributionThe right atrium in idiopathic hypereosinophilic syndrome: Insights from the 3D speckle tracking echocardiographic MAGYAR-Path Study
Original languageGerman
Pages (from-to)405-411
Number of pages7
Issue number5
Publication statusPublished - aug. 1 2019

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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