The effects of short-term exercise training on peak-torque are time- and fiber-type dependent

Dóra Ureczky, Gabriella Vácz, Andreas Costa, Bence Kopper, Z. Lacza, Tibor Hortobágyi, J. Tihanyi

Research output: Article

1 Citation (Scopus)

Abstract

We examined the susceptibility of fast and slow twitch muscle fibers in the quadriceps muscle to eccentric exercise-induced muscle damage. Nine healthy men (age: 22.5 ± 1.6 years) performed maximal eccentric quadriceps contractions at 120°·s-1 over a 120° of knee joint range of motion for ± consecutive days. Biopsies were taken from the vastus lateralis muscle before repeated bouts of eccentric exercise on the third and seventh day. Immunohistochemical procedures were used to determine fiber composition and fibronectin activity. Creatine kinase (CK) and lactate dehydrogenase (LDH) were determined in serum. Average torque was calculated in each day for each subject. Relative to baseline, average torque decreased 37.4% till day 3 and increased 43.0% from the day 3 to day ± (p <0.001). Creatine kinase and LDH were 70.6 and 1.5 times higher on day 3 and 75.5 and 1.4 times higher on day 6. Fibronectin was found in fast fibers in subjects with high CK level on day 3 and 7 after exercise, but on day 7, fibronectin seemed in both slow and fast fibers except in muscles of 2 subjects with high fast fiber percentage. Peak torque and muscle fiber-type composition measured at baseline showed a strong positive association on day 3 (r = 0.76, p <0.02) and strong negative association during recovery between day 3 and day ± (r = -0.76, p <0.02), and day 1 and day ± (r = 0.84, p <0.001). We conclude that the damage of fast fibers preceded the damage of slow fibers, and muscles with slow fiber dominance were more susceptible to repeated bouts of eccentric exercise than fast fiber dominance muscles. The data suggest that the responses to repeated bouts of eccentric exercise are fiber-type-dependent in the quadriceps muscle, which can be the basis for the design of individualized strength training protocols.

Original languageEnglish
Pages (from-to)2204-2213
Number of pages10
JournalJournal of Strength and Conditioning Research
Volume28
Issue number8
DOIs
Publication statusPublished - 2014

Fingerprint

Torque
Exercise
Muscles
Quadriceps Muscle
Creatine Kinase
Fibronectins
L-Lactate Dehydrogenase
Slow-Twitch Muscle Fibers
Fast-Twitch Muscle Fibers
Resistance Training
Knee Joint
Articular Range of Motion
Biopsy
Serum

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation
  • Medicine(all)

Cite this

The effects of short-term exercise training on peak-torque are time- and fiber-type dependent. / Ureczky, Dóra; Vácz, Gabriella; Costa, Andreas; Kopper, Bence; Lacza, Z.; Hortobágyi, Tibor; Tihanyi, J.

In: Journal of Strength and Conditioning Research, Vol. 28, No. 8, 2014, p. 2204-2213.

Research output: Article

Ureczky, Dóra ; Vácz, Gabriella ; Costa, Andreas ; Kopper, Bence ; Lacza, Z. ; Hortobágyi, Tibor ; Tihanyi, J. / The effects of short-term exercise training on peak-torque are time- and fiber-type dependent. In: Journal of Strength and Conditioning Research. 2014 ; Vol. 28, No. 8. pp. 2204-2213.
@article{32b9d4923d604c77aeca2fb3c5c7e681,
title = "The effects of short-term exercise training on peak-torque are time- and fiber-type dependent",
abstract = "We examined the susceptibility of fast and slow twitch muscle fibers in the quadriceps muscle to eccentric exercise-induced muscle damage. Nine healthy men (age: 22.5 ± 1.6 years) performed maximal eccentric quadriceps contractions at 120°·s-1 over a 120° of knee joint range of motion for ± consecutive days. Biopsies were taken from the vastus lateralis muscle before repeated bouts of eccentric exercise on the third and seventh day. Immunohistochemical procedures were used to determine fiber composition and fibronectin activity. Creatine kinase (CK) and lactate dehydrogenase (LDH) were determined in serum. Average torque was calculated in each day for each subject. Relative to baseline, average torque decreased 37.4{\%} till day 3 and increased 43.0{\%} from the day 3 to day ± (p <0.001). Creatine kinase and LDH were 70.6 and 1.5 times higher on day 3 and 75.5 and 1.4 times higher on day 6. Fibronectin was found in fast fibers in subjects with high CK level on day 3 and 7 after exercise, but on day 7, fibronectin seemed in both slow and fast fibers except in muscles of 2 subjects with high fast fiber percentage. Peak torque and muscle fiber-type composition measured at baseline showed a strong positive association on day 3 (r = 0.76, p <0.02) and strong negative association during recovery between day 3 and day ± (r = -0.76, p <0.02), and day 1 and day ± (r = 0.84, p <0.001). We conclude that the damage of fast fibers preceded the damage of slow fibers, and muscles with slow fiber dominance were more susceptible to repeated bouts of eccentric exercise than fast fiber dominance muscles. The data suggest that the responses to repeated bouts of eccentric exercise are fiber-type-dependent in the quadriceps muscle, which can be the basis for the design of individualized strength training protocols.",
keywords = "Eccentric exercise, Fiber composition, Fibronectin, Knee extensors, Muscle damage",
author = "D{\'o}ra Ureczky and Gabriella V{\'a}cz and Andreas Costa and Bence Kopper and Z. Lacza and Tibor Hortob{\'a}gyi and J. Tihanyi",
year = "2014",
doi = "10.1519/JSC.0000000000000414",
language = "English",
volume = "28",
pages = "2204--2213",
journal = "Strength and Conditioning Journal",
issn = "1524-1602",
publisher = "NSCA National Strength and Conditioning Association",
number = "8",

}

TY - JOUR

T1 - The effects of short-term exercise training on peak-torque are time- and fiber-type dependent

AU - Ureczky, Dóra

AU - Vácz, Gabriella

AU - Costa, Andreas

AU - Kopper, Bence

AU - Lacza, Z.

AU - Hortobágyi, Tibor

AU - Tihanyi, J.

PY - 2014

Y1 - 2014

N2 - We examined the susceptibility of fast and slow twitch muscle fibers in the quadriceps muscle to eccentric exercise-induced muscle damage. Nine healthy men (age: 22.5 ± 1.6 years) performed maximal eccentric quadriceps contractions at 120°·s-1 over a 120° of knee joint range of motion for ± consecutive days. Biopsies were taken from the vastus lateralis muscle before repeated bouts of eccentric exercise on the third and seventh day. Immunohistochemical procedures were used to determine fiber composition and fibronectin activity. Creatine kinase (CK) and lactate dehydrogenase (LDH) were determined in serum. Average torque was calculated in each day for each subject. Relative to baseline, average torque decreased 37.4% till day 3 and increased 43.0% from the day 3 to day ± (p <0.001). Creatine kinase and LDH were 70.6 and 1.5 times higher on day 3 and 75.5 and 1.4 times higher on day 6. Fibronectin was found in fast fibers in subjects with high CK level on day 3 and 7 after exercise, but on day 7, fibronectin seemed in both slow and fast fibers except in muscles of 2 subjects with high fast fiber percentage. Peak torque and muscle fiber-type composition measured at baseline showed a strong positive association on day 3 (r = 0.76, p <0.02) and strong negative association during recovery between day 3 and day ± (r = -0.76, p <0.02), and day 1 and day ± (r = 0.84, p <0.001). We conclude that the damage of fast fibers preceded the damage of slow fibers, and muscles with slow fiber dominance were more susceptible to repeated bouts of eccentric exercise than fast fiber dominance muscles. The data suggest that the responses to repeated bouts of eccentric exercise are fiber-type-dependent in the quadriceps muscle, which can be the basis for the design of individualized strength training protocols.

AB - We examined the susceptibility of fast and slow twitch muscle fibers in the quadriceps muscle to eccentric exercise-induced muscle damage. Nine healthy men (age: 22.5 ± 1.6 years) performed maximal eccentric quadriceps contractions at 120°·s-1 over a 120° of knee joint range of motion for ± consecutive days. Biopsies were taken from the vastus lateralis muscle before repeated bouts of eccentric exercise on the third and seventh day. Immunohistochemical procedures were used to determine fiber composition and fibronectin activity. Creatine kinase (CK) and lactate dehydrogenase (LDH) were determined in serum. Average torque was calculated in each day for each subject. Relative to baseline, average torque decreased 37.4% till day 3 and increased 43.0% from the day 3 to day ± (p <0.001). Creatine kinase and LDH were 70.6 and 1.5 times higher on day 3 and 75.5 and 1.4 times higher on day 6. Fibronectin was found in fast fibers in subjects with high CK level on day 3 and 7 after exercise, but on day 7, fibronectin seemed in both slow and fast fibers except in muscles of 2 subjects with high fast fiber percentage. Peak torque and muscle fiber-type composition measured at baseline showed a strong positive association on day 3 (r = 0.76, p <0.02) and strong negative association during recovery between day 3 and day ± (r = -0.76, p <0.02), and day 1 and day ± (r = 0.84, p <0.001). We conclude that the damage of fast fibers preceded the damage of slow fibers, and muscles with slow fiber dominance were more susceptible to repeated bouts of eccentric exercise than fast fiber dominance muscles. The data suggest that the responses to repeated bouts of eccentric exercise are fiber-type-dependent in the quadriceps muscle, which can be the basis for the design of individualized strength training protocols.

KW - Eccentric exercise

KW - Fiber composition

KW - Fibronectin

KW - Knee extensors

KW - Muscle damage

UR - http://www.scopus.com/inward/record.url?scp=84905822067&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84905822067&partnerID=8YFLogxK

U2 - 10.1519/JSC.0000000000000414

DO - 10.1519/JSC.0000000000000414

M3 - Article

C2 - 24531434

AN - SCOPUS:84905822067

VL - 28

SP - 2204

EP - 2213

JO - Strength and Conditioning Journal

JF - Strength and Conditioning Journal

SN - 1524-1602

IS - 8

ER -