The effects of probucol on QT QS2 relation and systolic time intervals

László Romics, László Littmann, Zoltán László, Tamás Fenyvesi

Research output: Article

9 Citations (Scopus)

Abstract

The QT, QTc, QS2 intervals, pre-ejection period-left ventricular ejection time ratios and serum lipoprotein levels were measured in 8 patients with primary hypercholesterolemia before and after a 3-month therapy with probucol, 1 g/day. Both QT and QTc intervals increased significantly, whereas no significant changes were observed between the pre- and post-treatment QT QS2 and pre-ejection period-left ventricular ejection time ratios. These results help to explain why treatment with probucol, while effecting a prolongation of the QTc interval, does not result in serious arrhythmias in man.

Original languageEnglish
Pages (from-to)303-308
Number of pages6
JournalInternational Journal of Cardiology
Volume19
Issue number3
DOIs
Publication statusPublished - jún. 1988

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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