The effect of Neydharting mud-pack therapy on knee osteoarthritis: A randomized, controlled, double-blind follow-up pilot study

Ildikó Katalin Tefner, Ramóna Gaál, András Koroknai, Adél Ráthonyi, Tamás Gáti, Péter Monduk, Edit Kiss, Csaba Kovács, G. Bálint, T. Bender

Research output: Article

26 Citations (Scopus)

Abstract

The aim of this study was to evaluate the effects of Neydharting mud-pack therapy on the clinical parameters and quality of life in patients with knee osteoarthritis. In this double-blind, randomized, follow-up study on 53 patients with knee osteoarthritis, one group received hot mud-pack therapy, whereas the other (control) group was treated with hot packs of a substance manufactured on 10 occasions for 2 weeks. Western Ontario and McMaster Universities Arthritis Index (WOMAC), EuroQoL-5D quality-of-life measure and need for analgesics and non-steroidal anti-inflammatory drugs were recorded before treatment, at the end of treatment (at Week 2), and at Weeks 6 and 12. The WOMAC and the EQ5D quality-of-life scores improved from the baseline to the end of treatment in both groups, and further improvement was observed during the follow-up period (p <0.001, respectively, in both groups). The need for medications for knee joint pain improved in both groups, and these changes were significant only in the mud-treated group (p <0.001), but not in the control group (p = 0.106) compared to baseline. The number of patients requiring medications for knee joint pain showed a continuous downward trend at the subsequent post-treatment visits by the mud-treated group, and these changes became significant by Visit 4 compared to baseline (p = 0.016). The control group showed only temporary and not significant decrease. The difference was not significant between the groups in any of the outcome parameters at any visits. The Neydharting mud pack has a favorable effect on the clinical parameters, quality of life, and need for medications in patients with knee osteoarthritis. To evaluate the chemical effect, the number of patients should be increased.

Original languageEnglish
Pages (from-to)2569-2576
Number of pages8
JournalRheumatology International
Volume33
Issue number10
DOIs
Publication statusPublished - okt. 2013

Fingerprint

Mud Therapy
Knee Osteoarthritis
Quality of Life
Arthralgia
Knee Joint
Control Groups
Ontario
Therapeutics
Arthritis
Analgesics
Anti-Inflammatory Agents
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Rheumatology
  • Immunology
  • Immunology and Allergy

Cite this

The effect of Neydharting mud-pack therapy on knee osteoarthritis : A randomized, controlled, double-blind follow-up pilot study. / Tefner, Ildikó Katalin; Gaál, Ramóna; Koroknai, András; Ráthonyi, Adél; Gáti, Tamás; Monduk, Péter; Kiss, Edit; Kovács, Csaba; Bálint, G.; Bender, T.

In: Rheumatology International, Vol. 33, No. 10, 10.2013, p. 2569-2576.

Research output: Article

Tefner, Ildikó Katalin ; Gaál, Ramóna ; Koroknai, András ; Ráthonyi, Adél ; Gáti, Tamás ; Monduk, Péter ; Kiss, Edit ; Kovács, Csaba ; Bálint, G. ; Bender, T. / The effect of Neydharting mud-pack therapy on knee osteoarthritis : A randomized, controlled, double-blind follow-up pilot study. In: Rheumatology International. 2013 ; Vol. 33, No. 10. pp. 2569-2576.
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abstract = "The aim of this study was to evaluate the effects of Neydharting mud-pack therapy on the clinical parameters and quality of life in patients with knee osteoarthritis. In this double-blind, randomized, follow-up study on 53 patients with knee osteoarthritis, one group received hot mud-pack therapy, whereas the other (control) group was treated with hot packs of a substance manufactured on 10 occasions for 2 weeks. Western Ontario and McMaster Universities Arthritis Index (WOMAC), EuroQoL-5D quality-of-life measure and need for analgesics and non-steroidal anti-inflammatory drugs were recorded before treatment, at the end of treatment (at Week 2), and at Weeks 6 and 12. The WOMAC and the EQ5D quality-of-life scores improved from the baseline to the end of treatment in both groups, and further improvement was observed during the follow-up period (p <0.001, respectively, in both groups). The need for medications for knee joint pain improved in both groups, and these changes were significant only in the mud-treated group (p <0.001), but not in the control group (p = 0.106) compared to baseline. The number of patients requiring medications for knee joint pain showed a continuous downward trend at the subsequent post-treatment visits by the mud-treated group, and these changes became significant by Visit 4 compared to baseline (p = 0.016). The control group showed only temporary and not significant decrease. The difference was not significant between the groups in any of the outcome parameters at any visits. The Neydharting mud pack has a favorable effect on the clinical parameters, quality of life, and need for medications in patients with knee osteoarthritis. To evaluate the chemical effect, the number of patients should be increased.",
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