Synthesis of Vinca Alkaloids and Related Compounds. 21. Preparation of (±)-Eburnamonine, (±)-3-Epieburnamonine, and (±)-C-Norquebrachamine from a Common Intermediate

Györev Kalaus, Numan Malkieh, Ildikó Katona, Alajos Kálmán, Lajos Szabó, Csaba Szántay, MáRia Kaitár-Peredv, Tibor Koritsánszkv

Research output: Article

28 Citations (Scopus)

Abstract

The pentacyclic indole derivatives (±)-eburnamonine (8b) and (±)-3-epieburnamonine (17b) and the tetracyclic (±)-C-norquebrachamine (10) have been synthesized from the easily available common intermediate 2a. In the course of the syntheses some unexpected transformations were observed. Structure elucidations of new products were performed partly by X-ray analysis.

Original languageEnglish
Pages (from-to)3760-3767
Number of pages8
JournalJournal of Organic Chemistry
Volume50
Issue number20
DOIs
Publication statusPublished - okt. 1985

ASJC Scopus subject areas

  • Organic Chemistry

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