Synthesis of magnetic nanoparticles and magnetic fluids for biomedical applications

L. Vékás, E. Tombácz, Rodica Turcu, I. Morjan, M. V. Avdeev, Theodora Krasia Christoforou, V. Socoliuc

Research output: Chapter

6 Citations (Scopus)

Abstract

Chemical coprecipitation and gas-phase laser pyrolysis procedures were applied to obtain various iron-based magnetic nanoparticles (magnetite, maghemite, and carbon layer-coated iron) in the size range of 3-15 nm used as basic building blocks for functionalized coreshell particles, magnetic nanofluids, as well as multifunctional hybrid nanostructures based on stimuli-responsive biocompatible polymers and block copolymers. The particle size distribution, magnetostatic properties, surface coating efficiency, and embedding/encapsulation mechanisms of magnetic nanoparticles and particle clusters in various biocompatible polymer matrices (core-shell nanostructures, microgels, and micelles) were examined by TEM/HRTEM, vibrational sample magnetometry, dynamic light scattering, Fourier transform infrared spectroscopy, and small-angle neutron scattering. The novel magnetic hybrid nanostructured materials envisaged for MRI contrast agents, magnetic carriers in bioseparation equipment, or magnetothermally triggered drug delivery systems have superparamagnetic behavior and exhibit magnetoand thermoresponsive properties, high stability, and in vitro biocompatibility.

Original languageEnglish
Title of host publicationNanomedicine - Basic and Clinical Applications in Diagnostics and Therapy
PublisherS. Karger AG
Pages35-52
Number of pages18
ISBN (Print)9783805598194, 9783805598187
DOIs
Publication statusPublished - okt. 6 2011

Fingerprint

Magnetic fluids
Nanostructures
Nanoparticles
Magnetite Nanoparticles
Iron
Magnetostatics
Hybrid materials
Polymers
Micelles
Magnetometry
Dynamic light scattering
Coprecipitation
Neutron scattering
Polymer matrix
Biocompatibility
Encapsulation
Nanostructured materials
Particle size analysis
Magnetic resonance imaging
Small Angle Scattering

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Vékás, L., Tombácz, E., Turcu, R., Morjan, I., Avdeev, M. V., Christoforou, T. K., & Socoliuc, V. (2011). Synthesis of magnetic nanoparticles and magnetic fluids for biomedical applications. In Nanomedicine - Basic and Clinical Applications in Diagnostics and Therapy (pp. 35-52). S. Karger AG. https://doi.org/10.1002/9783805598194.ch3

Synthesis of magnetic nanoparticles and magnetic fluids for biomedical applications. / Vékás, L.; Tombácz, E.; Turcu, Rodica; Morjan, I.; Avdeev, M. V.; Christoforou, Theodora Krasia; Socoliuc, V.

Nanomedicine - Basic and Clinical Applications in Diagnostics and Therapy. S. Karger AG, 2011. p. 35-52.

Research output: Chapter

Vékás, L, Tombácz, E, Turcu, R, Morjan, I, Avdeev, MV, Christoforou, TK & Socoliuc, V 2011, Synthesis of magnetic nanoparticles and magnetic fluids for biomedical applications. in Nanomedicine - Basic and Clinical Applications in Diagnostics and Therapy. S. Karger AG, pp. 35-52. https://doi.org/10.1002/9783805598194.ch3
Vékás L, Tombácz E, Turcu R, Morjan I, Avdeev MV, Christoforou TK et al. Synthesis of magnetic nanoparticles and magnetic fluids for biomedical applications. In Nanomedicine - Basic and Clinical Applications in Diagnostics and Therapy. S. Karger AG. 2011. p. 35-52 https://doi.org/10.1002/9783805598194.ch3
Vékás, L. ; Tombácz, E. ; Turcu, Rodica ; Morjan, I. ; Avdeev, M. V. ; Christoforou, Theodora Krasia ; Socoliuc, V. / Synthesis of magnetic nanoparticles and magnetic fluids for biomedical applications. Nanomedicine - Basic and Clinical Applications in Diagnostics and Therapy. S. Karger AG, 2011. pp. 35-52
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