Synthesis and specific tritium labelling of the behaviourally active octapeptide des‐9‐glycinamide‐lysine‐vasopressin in two different aminoacid residues

Gy Kéri, I. Teplán

Research output: Article

4 Citations (Scopus)

Abstract

The specific labelling of the octapeptide, des‐9‐glycinamide‐8‐lysine‐vasopressin in the tyrosine and phenylalanine3 residues with tritium is described. The 3.5‐dibromotyrosine and 4‐chloro‐phenylalanine containing precursor peptides for labelling were synthesized by solid phase peptide synthesis. These peptides were catalytically tritiated giving the labelled derivatives with high specific radioactivity.

Original languageEnglish
Pages (from-to)163-168
Number of pages6
JournalJournal of Labelled Compounds and Radiopharmaceuticals
Volume15
Issue number1 S
DOIs
Publication statusPublished - okt. 1978

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ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Radiology Nuclear Medicine and imaging
  • Drug Discovery
  • Spectroscopy
  • Organic Chemistry

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