Abstract
Tuberous sclerosis complex (TSC) is an autosomal dominant disease due to the uncontrolled differentiation, proliferation, and migration of cells in several organs. Clinical expression is highly variable, from mild skin findings and asymptomatic brain lesions to seizures, mental retardation, autism, and potentially fatal kidney, cardiac, or pulmonary disease. Aim of this paper is to summarize the diagnostic criteria, surveillance and therapeutic issues of this multisystemic disorder emphasizing the most important neurological consequences. Presenting the state-of-The-Art management recommendations and comparing them with the local protocols, we hope that our review might help in the proper assessment of one of the most important single gene disorder.
| Original language | English |
|---|---|
| Pages (from-to) | 97-103 |
| Number of pages | 7 |
| Journal | Ideggyogyaszati Szemle |
| Volume | 70 |
| Issue number | 3-4 |
| DOIs | |
| Publication status | Published - márc. 30 2017 |
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ASJC Scopus subject areas
- Neurology
- Clinical Neurology
Cite this
Surveillance and management of patients with tuberous sclerosis complex. / Fogarasi, A.; Gyorsok, Zsuzsanna; Bodó, Ti'mea.
In: Ideggyogyaszati Szemle, Vol. 70, No. 3-4, 30.03.2017, p. 97-103.Research output: Article
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TY - JOUR
T1 - Surveillance and management of patients with tuberous sclerosis complex
AU - Fogarasi, A.
AU - Gyorsok, Zsuzsanna
AU - Bodó, Ti'mea
PY - 2017/3/30
Y1 - 2017/3/30
N2 - Tuberous sclerosis complex (TSC) is an autosomal dominant disease due to the uncontrolled differentiation, proliferation, and migration of cells in several organs. Clinical expression is highly variable, from mild skin findings and asymptomatic brain lesions to seizures, mental retardation, autism, and potentially fatal kidney, cardiac, or pulmonary disease. Aim of this paper is to summarize the diagnostic criteria, surveillance and therapeutic issues of this multisystemic disorder emphasizing the most important neurological consequences. Presenting the state-of-The-Art management recommendations and comparing them with the local protocols, we hope that our review might help in the proper assessment of one of the most important single gene disorder.
AB - Tuberous sclerosis complex (TSC) is an autosomal dominant disease due to the uncontrolled differentiation, proliferation, and migration of cells in several organs. Clinical expression is highly variable, from mild skin findings and asymptomatic brain lesions to seizures, mental retardation, autism, and potentially fatal kidney, cardiac, or pulmonary disease. Aim of this paper is to summarize the diagnostic criteria, surveillance and therapeutic issues of this multisystemic disorder emphasizing the most important neurological consequences. Presenting the state-of-The-Art management recommendations and comparing them with the local protocols, we hope that our review might help in the proper assessment of one of the most important single gene disorder.
KW - Manogement guidelines
KW - Surveillance
KW - Therapy
KW - Tuberous sclerosis complex
UR - http://www.scopus.com/inward/record.url?scp=85018854746&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85018854746&partnerID=8YFLogxK
U2 - 10.18071/isz.70.0097
DO - 10.18071/isz.70.0097
M3 - Article
C2 - 29870614
AN - SCOPUS:85018854746
VL - 70
SP - 97
EP - 103
JO - Ideggyogyaszati Szemle
JF - Ideggyogyaszati Szemle
SN - 0019-1442
IS - 3-4
ER -