Studying solution-kinetic of magnesium-oxide containing granules produced by laboratory scale fluidization

I. Rácz, R. Zelkó, E. Bihari

Research output: Article

3 Citations (Scopus)

Abstract

In practice of manufacturing industrial pharmaceutical products, the technique of fluidization has been used extensively in the past decades. The authors studied the magnesium oxide-containing granulates made by fluidization granulation in laboratory, to optimize the process, to determine the neutralization kinetic parameters of granulates, to establish the connections between the method of granulation and the release of active substances. According to our findings, the pharmaceutical product's characteristics in the aspects of physics, chemistry, stability and bioavailability may remarkably change without fixing the border conditions of parameters within limits.

Original languageEnglish
Pages (from-to)175-178
Number of pages4
JournalActa Pharmaceutica Hungarica
Volume64
Issue number5
Publication statusPublished - 1994

Fingerprint

Magnesium Oxide
Physics
Pharmaceutical Preparations
Biological Availability

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

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abstract = "In practice of manufacturing industrial pharmaceutical products, the technique of fluidization has been used extensively in the past decades. The authors studied the magnesium oxide-containing granulates made by fluidization granulation in laboratory, to optimize the process, to determine the neutralization kinetic parameters of granulates, to establish the connections between the method of granulation and the release of active substances. According to our findings, the pharmaceutical product's characteristics in the aspects of physics, chemistry, stability and bioavailability may remarkably change without fixing the border conditions of parameters within limits.",
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