Study of diastereomeric thioureas formed with a new chiral derivatizing agent

M. Péter, A. Perjéssy, D. Loos, F. Fülöp

Research output: Article

1 Citation (Scopus)

Abstract

(1S,2S)-1,3-Diacetoxy-1-(4-nitrophenyl)-2-propyl isothiocyanate ((S,S)-DANI) was recently introduced as a new chiral derivatizing agent for the enantioseparation of amino compounds. In the present study, diastereomeric derivatives of racemic amino acids were formed with (S,S)-DANI. The thioureas produced were distinguished by means of infrared spectroscopy, theoretical calculations and high-performance liquid chromatography. The differences observed between the corresponding diastereomers by the independent methods are considered to prove the applicability of the new reagent in the field of enantiomer separation.

Original languageEnglish
Pages (from-to)525-534
Number of pages10
JournalEnantiomer
Volume5
Issue number6
Publication statusPublished - 2000

Fingerprint

Thiourea
Enantiomers
High performance liquid chromatography
Infrared spectroscopy
Spectrum Analysis
High Pressure Liquid Chromatography
Derivatives
Amino Acids
4-nitrophenyl
isothiocyanic acid

ASJC Scopus subject areas

  • Chemistry(all)
  • Organic Chemistry
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry

Cite this

Study of diastereomeric thioureas formed with a new chiral derivatizing agent. / Péter, M.; Perjéssy, A.; Loos, D.; Fülöp, F.

In: Enantiomer, Vol. 5, No. 6, 2000, p. 525-534.

Research output: Article

Péter, M, Perjéssy, A, Loos, D & Fülöp, F 2000, 'Study of diastereomeric thioureas formed with a new chiral derivatizing agent', Enantiomer, vol. 5, no. 6, pp. 525-534.
Péter, M. ; Perjéssy, A. ; Loos, D. ; Fülöp, F. / Study of diastereomeric thioureas formed with a new chiral derivatizing agent. In: Enantiomer. 2000 ; Vol. 5, No. 6. pp. 525-534.
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