Structural analysis of w/o/w multiple emulsions by means of DSC

Anita Kovács, I. Csóka, Magdolna Kónya, E. Csányi, A. Fehér, I. Eros

Research output: Article

18 Citations (Scopus)

Abstract

The properties of the inner and the external aqueous phases, were studied in w/o/w multiple emulsions with light microscopic image analysis and differential scanning calorimetry (DSC). The importance of multiple emulsions lies in the presence of these aqueous phases, making them available for sustained, controlled drug delivery systems. Differentiation of these two aqueous phases, studying the effect of manufacturing technology on droplet structure, quantitative determination of phase volumes and any changes occurring during storage are essential when planning w/o/w emulsions. The present study uses microscopic observations combined with DSC measurements in order to identify the formed structure, at developmental stage in case of different components, preparation methods, and stirring rates. These tools are beneficial during manufacturing as in process controls, or to ensure product quality.

Original languageEnglish
Pages (from-to)491-497
Number of pages7
JournalJournal of Thermal Analysis and Calorimetry
Volume82
Issue number2
DOIs
Publication statusPublished - nov. 1 2005

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ASJC Scopus subject areas

  • Condensed Matter Physics
  • Physical and Theoretical Chemistry

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