Strategic Application of Residence-Time Control in Continuous-Flow Reactors

István M. Mándity, Sándor B. Ötvös, Ferenc Fülöp

Research output: Article

46 Citations (Scopus)


As a sustainable alternative for conventional batch-based synthetic techniques, the concept of continuous-flow processing has emerged in the synthesis of fine chemicals. Systematic tuning of the residence time, a key parameter of continuous-reaction technology, can govern the outcome of a chemical reaction by determining the reaction rate and the conversion and by influencing the product selectivity. This review furnishes a brief insight into flow reactions in which high chemo- and/or stereoselectivity can be attained by strategic residence-time control and illustrates the importance of the residence time as a crucial parameter in sustainable method development. Such a fine reaction control cannot be performed in conventional batch reaction set-ups.

Original languageEnglish
Pages (from-to)212-223
Number of pages12
Issue number3
Publication statusPublished - jún. 1 2015

ASJC Scopus subject areas

  • Chemistry(all)

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