Stereo- and regiocontrolled synthesis of highly functionalized cyclopentanes with multiple chiral centers

Melinda Nonn, Adrienn Binder, Balázs Volk, Loránd Kiss

Research output: Article

1 Citation (Scopus)

Abstract

The synthesis of some highly substituted three-dimensional cyclopentanes with multiple chiral centers and with high regiochemical and stereochemical diversity has been accomplished starting from cyclopentadiene-derived aminocyclopentenecarboxylic acids. The small-molecular design consisted of stereo- and regiocontrolled functionalization of the starting cyclopentene β- and γ-amino acids through oxirane formation/oxirane opening and afforded regio- and diastereoisomers of orthogonally protected aminocyclopentanecarboxylates.

Original languageEnglish
Pages (from-to)1199-1209
Number of pages11
JournalSynthetic Communications
Volume50
Issue number8
DOIs
Publication statusPublished - ápr. 17 2020

ASJC Scopus subject areas

  • Organic Chemistry

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