Stabilisation of peptide foldamers in an aqueous medium by incorporation of azapeptide building blocks

Research output: Article

25 Citations (Scopus)

Abstract

Stable foldamers in water: Helical peptidic foldamers including H12 and H10/12 helices were constructed and stabilised in water. The foldamers' extra rigidity stems from the strong hydrogen bonding network of the azapeptide groups (see graphic).

Original languageEnglish
Pages (from-to)10736-10741
Number of pages6
JournalChemistry - A European Journal
Volume15
Issue number41
DOIs
Publication statusPublished - okt. 19 2009

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ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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