Simple, quick methods for detection of 6-amino-penicillanic acid

Research output: Article

6 Citations (Scopus)

Abstract

ONE of the greatest discoveries of the past years in penicillin research was the discovery, isolation1 and preparation of 6-amino-penicillanic acid (6-APA) forming the common 'nucleus' of natural penicillins2,3, and the successful introduction into therapy of semi-synthetic penicillins produced from it4,5. The new semi-synthetic penicillin preparations have already made great progress in the fight against resistant bacteria. The possibility is now laid open for the preparation of penicillins possessing novel effectiveness6. The basis for efforts of this kind is 6-APA research, and its quick identification in fermentation liquor and other reaction mixtures.

Original languageEnglish
Pages (from-to)1223
Number of pages1
JournalNature
Volume191
Issue number4794
DOIs
Publication statusPublished - 1961

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Penicillanic Acid
Penicillins
Amino Acids
Research
Fermentation
Bacteria

ASJC Scopus subject areas

  • General

Cite this

Simple, quick methods for detection of 6-amino-penicillanic acid. / Uri, J.; Sztaricskai, F.

In: Nature, Vol. 191, No. 4794, 1961, p. 1223.

Research output: Article

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