The authors - analysing the data of 81 salvage retroperitoneal lymphnode dissections - have examined the role of different surgical-pathological factors in the surgical management of patients with advanced testicular tumors (UICC stage II/B bulky and stage III). From 100 men with advanced germ cell testicular tumors have been treated with 4-5 courses of inductive chemotherapy were referred to salvage retroperitoneal lymphnode dissection with complete and partial remission too. After evaluating their data, they concluded, that beside the well known primary role of the residual histology (active cancer in the retroperitoneal rest) in prognosis, they proved, the role of retroperitoneal lymphnode dissection was far more decisive in the treatment of patients entered partial remission after inductive chemotherapy. They found a 17% incidence of active cancer in the retroperitoneum of complete remission cases too. In contrast to tile general belief, they have proved, if a patient needs more than 4 courses of combination chemotherapy, or mainly if it has to be completed by a second, or a third line combination to reach a clinical partial remission in the retroperitoneum, it was a bad prognostic sign, pointing to a chemoresistant retroperitoneal rest.
|Translated title of the contribution||Significance and correlation of different prognostic factors in the surgical management of germ cell testicular tumors in advanced stages|
|Number of pages||9|
|Publication status||Published - dec. 1 1994|
- Retroperitoneal lymphnode dissection
- Testicular tumors
ASJC Scopus subject areas