Serum proteins in processes associated with an increase in the monoclonal and polyclonal immunoglobulin levels

L. Jakab, S. Fekete, K. Cseh, Sz Benedek

Research output: Article

1 Citation (Scopus)

Abstract

The sera of patients with IgG-myeloma, IgM-macroglobulinaemia and with processes accompanied by high polyclonal Ig-levels were measured by radial immunodiffusion for immunoglobulins, coeruloplasmin, α-2-macroglobulin, C3-component, transferrin, α-1-antitrypsin, α-2-haptoglobin and haemopexin. In the presence of typical changes in the immunoglobulin concentrations, elevation of α-2-macroglobulin was found only if polyclonal Ig was increased. The concentration of the C3 component was reduced only in IgM macroglobulinaemia, that of transferrin only in IgG-myeloma, that of α-2-haptoglobin only in IgM-macroglobulinaemia and in case of increased polyclonal Ig.

Original languageEnglish
Pages (from-to)261-267
Number of pages7
JournalActa Medica Academiae Scientiarum Hungaricae
Volume37
Issue number3
Publication statusPublished - 1980

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Waldenstrom Macroglobulinemia
Immunoglobulin M
Immunoglobulins
Blood Proteins
Macroglobulins
Haptoglobins
Transferrin
Immunoglobulin G
Hemopexin
Immunodiffusion
Serum

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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AU - Fekete, S.

AU - Cseh, K.

AU - Benedek, Sz

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AB - The sera of patients with IgG-myeloma, IgM-macroglobulinaemia and with processes accompanied by high polyclonal Ig-levels were measured by radial immunodiffusion for immunoglobulins, coeruloplasmin, α-2-macroglobulin, C3-component, transferrin, α-1-antitrypsin, α-2-haptoglobin and haemopexin. In the presence of typical changes in the immunoglobulin concentrations, elevation of α-2-macroglobulin was found only if polyclonal Ig was increased. The concentration of the C3 component was reduced only in IgM macroglobulinaemia, that of transferrin only in IgG-myeloma, that of α-2-haptoglobin only in IgM-macroglobulinaemia and in case of increased polyclonal Ig.

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