Serologic assays specific to immunoglobulin M antibodies against hepatitis E virus: Pangenotypic evaluation of performances

Jan Drobeniuc, Jihong Meng, Gábor Reuter, Tracy Greene-Montfort, Natasha Khudyakova, Zoya Dimitrova, Saleem Kamili, Chong Gee Teo

Research output: Article

133 Citations (Scopus)

Abstract

Six immunoassays for detecting immunoglobulin M antibodies to hepatitis E virus were evaluated. Serum samples representing acute infection by each of the 4 viral genotypes as well as nonacute hepatitis E virus infection constituted the test panels. Diagnostic sensitivities and specificities as well as interassay agreement varied widely. Analytical sensitivity limits also were determined and were found to be particularly disparate.

Original languageEnglish
Pages (from-to)e24-e27
JournalClinical Infectious Diseases
Volume51
Issue number3
DOIs
Publication statusPublished - aug. 1 2010

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ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Drobeniuc, J., Meng, J., Reuter, G., Greene-Montfort, T., Khudyakova, N., Dimitrova, Z., Kamili, S., & Teo, C. G. (2010). Serologic assays specific to immunoglobulin M antibodies against hepatitis E virus: Pangenotypic evaluation of performances. Clinical Infectious Diseases, 51(3), e24-e27. https://doi.org/10.1086/654801