Sequencing and molecular modeling identifies candidate members of Caliciviridae family in bats

Gábor Kemenesi, Ákos Gellért, Bianka Dallos, Tamás Görföl, Sándor Boldogh, Péter Estók, Szilvia Marton, Miklós Oldal, Vito Martella, Krisztián Bányai, Ferenc Jakab

Research output: Article

6 Citations (Scopus)

Abstract

Emerging viral diseases represent an ongoing challenge for globalized world and bats constitute an immense, partially explored, reservoir of potentially zoonotic viruses. Caliciviruses are important human and animal pathogens and, as observed for human noroviruses, they may impact on human health on a global scale. By screening fecal samples of bats in Hungary, calicivirus RNA was identified in the samples of Myotis daubentonii and Eptesicus serotinus bats. In order to characterize more in detail the bat caliciviruses, large portions of the genome sequence of the viruses were determined. Phylogenetic analyses and molecular modeling identified firmly the two viruses as candidate members within the Caliciviridae family, with one calicivirus strain resembling members of the Sapovirus genus and the other bat calicivirus being more related to porcine caliciviruses of the proposed genus Valovirus. This data serves the effort for detecting reservoir hosts for potential emerging viruses and recognize important evolutionary relationships.

Original languageEnglish
Pages (from-to)227-232
Number of pages6
JournalInfection, Genetics and Evolution
Volume41
DOIs
Publication statusPublished - júl. 1 2016

ASJC Scopus subject areas

  • Microbiology
  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Genetics
  • Microbiology (medical)
  • Infectious Diseases

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    Kemenesi, G., Gellért, Á., Dallos, B., Görföl, T., Boldogh, S., Estók, P., Marton, S., Oldal, M., Martella, V., Bányai, K., & Jakab, F. (2016). Sequencing and molecular modeling identifies candidate members of Caliciviridae family in bats. Infection, Genetics and Evolution, 41, 227-232. https://doi.org/10.1016/j.meegid.2016.04.004