Selective O-alkylations with glycol chlorohydrins via the Mitsunobu reaction. A versatile route to calix[4]- and 1,1′-binaphthocrowns

Research output: Article

10 Citations (Scopus)

Abstract

Selective monoalkylation of p-tert-butylcalix[4]arene and BINOL with oligoethylene glycol chlorohydrins was achieved under the Mitsunobu protocol using DEAD/TPP. The method provides a simple access to ether precursors capable of cyclising to various crowns.

Original languageEnglish
Pages (from-to)5041-5048
Number of pages8
JournalTetrahedron
Volume60
Issue number23
DOIs
Publication statusPublished - máj. 31 2004

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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