Selective heterogeneous catalytic hydrogenation of nitriles to primary amines in liquid phase: Part I. Hydrogenation of benzonitrile over palladium

László Hegedus, Tibor Máthé

Research output: Article

65 Citations (Scopus)

Abstract

A method for selective liquid-phase heterogeneous catalytic hydrogenation of nitriles to primary amines has been developed. Benzonitrile (BN) was hydrogenated to benzylamine (BA) under mild reaction conditions (30 °C, 6 bar), over supported palladium catalysts, in a mixture of two immiscible solvents (e.g. water/dichloromethane) and in the presence of sodium dihydrogen phosphate (NaH2PO4). Complete conversion, very high selectivity (95% to BA) and isolated yield (85-90%) could be achieved by using this process. Very pure product (>99% BA-content) was prepared without applying any special purification procedures.

Original languageEnglish
Pages (from-to)209-215
Number of pages7
JournalApplied Catalysis A: General
Volume296
Issue number2
DOIs
Publication statusPublished - dec. 12 2005

ASJC Scopus subject areas

  • Catalysis
  • Process Chemistry and Technology

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