Reliability of immunocytochemistry and fluorescence in situ hybridization on fine-needle aspiration cytology samples of breast cancers: A comparative study

Balazs Acs, Nora Szekely, A. Szász, G. Lotz, Tamas Szekely, Roland Istok, Eszter Szekely, Lilla Madaras, J. Kulka, Balazs Jaray

Research output: Article

4 Citations (Scopus)


Introduction: To characterize breast tumors and metastases, fine-needle aspiration cytology (FNAB) can be a favorable first choice. However, the diagnostic accuracy of ancillary tests applied to FNAB samples is yet to be validated. Patients and Methods: We examined 110 breast cancer patients' paired cytological and surgical resection specimens evaluated between 2005 and 2014. Comparison of ER and Her2 immunocytochemical (ICC) and immunohistochemical (IHC) staining and HER2 fluorescence in situ hybridization (FISH) was performed. Results: Significant difference (p

Original languageEnglish
JournalDiagnostic Cytopathology
Publication statusAccepted/In press - 2016


ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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