Related topic: Use of PAMPA and artificial membranes

Bálint Sinkó, K. Takács-Novák

Research output: Chapter

Abstract

The following paragraphs describe the options of applying artificial membranes for the prediction of transdermal penetration, focusing mostly on the PAMPA method. A model membrane of PAMPA mimicking skin penetration was first described in 2006, but the need for a more bio-mimetic system has arisen with new industrial tendencies, and a more bio-relevant system was published in 2012. Since its first publication, Skin PAMPA has already been applied by several universities and industrial groups successfully and the first articles, podium, and poster presentations have appeared. Application of the Skin PAMPA model has been extended and examples for testing of semi-solid formulations and transdermal patches are available, besides the standard solution applications.

Original languageEnglish
Title of host publicationSkin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds
PublisherSpringer Japan
Pages391-397
Number of pages7
ISBN (Electronic)9784431565260
ISBN (Print)9784431565246
DOIs
Publication statusPublished - nov. 28 2017

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ASJC Scopus subject areas

  • Medicine(all)
  • Chemistry(all)

Cite this

Sinkó, B., & Takács-Novák, K. (2017). Related topic: Use of PAMPA and artificial membranes. In Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds (pp. 391-397). Springer Japan. https://doi.org/10.1007/978-4-431-56526-0_35