Redox status of dogs with non-hodgkin lymphomas. An ESR study

Péter Vajdovich, Tamás Kriska, M. Mézes, Piroska Ribiczey Szabó, Nándor Balogh, András Bánfi, Attila Arany-Tóth, Tibor Gaál, J. Jakus

Research output: Article

13 Citations (Scopus)

Abstract

Free radical and antioxidant parameters in healthy dogs (n=10) and dogs with non-Hodgkin lymphomas (n=11) were measured in blood and lymph node tissue samples before chemotherapy. Enzymatic and other biochemical measurements were performed. We found that (i) free radical concentrations based on ESR spectra of tissues correlated with higher proliferative character; (ii) lymphoma cases showed an impaired antioxidant status; (iii) tumors with low oxidative burst capacity and higher reduced/oxidized glutathione ratio responded better to chemotherapy; and (iv) affected blood and lymph nodes were under strong oxidative stress.

Original languageEnglish
Pages (from-to)339-346
Number of pages8
JournalCancer Letters
Volume224
Issue number2
DOIs
Publication statusPublished - jún. 28 2005

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Non-Hodgkin's Lymphoma
Oxidation-Reduction
Free Radicals
Antioxidants
Lymph Nodes
Dogs
Drug Therapy
Respiratory Burst
Glutathione Disulfide
Glutathione
Lymphoma
Oxidative Stress
Neoplasms

ASJC Scopus subject areas

  • Cancer Research
  • Molecular Biology
  • Oncology

Cite this

Redox status of dogs with non-hodgkin lymphomas. An ESR study. / Vajdovich, Péter; Kriska, Tamás; Mézes, M.; Szabó, Piroska Ribiczey; Balogh, Nándor; Bánfi, András; Arany-Tóth, Attila; Gaál, Tibor; Jakus, J.

In: Cancer Letters, Vol. 224, No. 2, 28.06.2005, p. 339-346.

Research output: Article

Vajdovich, P, Kriska, T, Mézes, M, Szabó, PR, Balogh, N, Bánfi, A, Arany-Tóth, A, Gaál, T & Jakus, J 2005, 'Redox status of dogs with non-hodgkin lymphomas. An ESR study', Cancer Letters, vol. 224, no. 2, pp. 339-346. https://doi.org/10.1016/j.canlet.2004.11.037
Vajdovich P, Kriska T, Mézes M, Szabó PR, Balogh N, Bánfi A et al. Redox status of dogs with non-hodgkin lymphomas. An ESR study. Cancer Letters. 2005 jún. 28;224(2):339-346. https://doi.org/10.1016/j.canlet.2004.11.037
Vajdovich, Péter ; Kriska, Tamás ; Mézes, M. ; Szabó, Piroska Ribiczey ; Balogh, Nándor ; Bánfi, András ; Arany-Tóth, Attila ; Gaál, Tibor ; Jakus, J. / Redox status of dogs with non-hodgkin lymphomas. An ESR study. In: Cancer Letters. 2005 ; Vol. 224, No. 2. pp. 339-346.
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