Rapid, simple, and efficient deprotection of benzyl/benzylidene protected carbohydrates by utilization of flow chemistry

Filip S. Ekholm, István M. Mándity, Ferenc Fülöp, Reko Leino

Research output: Article

14 Citations (Scopus)

Abstract

A rapid, simple, and efficient deprotection procedure for the deprotection of benzyl- and/or benzylidene protected carbohydrates is described utilizing a continuous flow hydrogenation reactor. The method tolerates both acid- and base sensitive functional groups. The high efficiency, simple work-up, and short reaction time should make this method appealing to researchers working in the fields of carbohydrate chemistry and total synthesis.

Original languageEnglish
Pages (from-to)1839-1841
Number of pages3
JournalTetrahedron Letters
Volume52
Issue number16
DOIs
Publication statusPublished - ápr. 20 2011

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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