Propofol 1% versus propofol 2% in children undergoing minor ENT surgery

Michel Pellégrini, C. Lysakowski, L. Dumont, A. Borgeat, E. Tassonyi

Research output: Article

7 Citations (Scopus)

Abstract

Background. The induction characteristics of propofol 1% and 2% were compared in children undergoing ENT surgery, in a prospective, randomized, double-blind study. Methods. One hundred and eight children received propofol 1% (n=55) or 2% (n=53) for induction and maintenance of anaesthesia. For induction, propofol 4 mg kg-1 was injected at a constant rate (1200 ml h-1), supplemented with alfentanil. Intubating conditions without the use of a neuromuscular blocking agent were scored. Results. Pain on injection occurred in 9% and 21% of patients after propofol 1% and 2%, respectively (P=0.09). Loss of consciousness was more rapid with propofol 2% compared with propofol 1% (47 s vs 54 s; P=0.02). Spontaneous movements during induction occurred in 22% and 34% (P=0.18), and intubating conditions were satisfactory in 87% and 96% (P=0.19) of children receiving propofol 1% or 2%, respectively. There were no differences between the two groups in respect of haemodynamic changes or adverse events. Conclusions. For the end-points tested, propofol 1% and propofol 2% are similar for induction of anaesthesia in children undergoing minor ENT surgery.

Original languageEnglish
Pages (from-to)375-377
Number of pages3
JournalBritish Journal of Anaesthesia
Volume90
Issue number3
DOIs
Publication statusPublished - márc. 1 2003

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Minor Surgical Procedures
Propofol
Anesthesia
Alfentanil
Neuromuscular Blocking Agents
Unconsciousness
Double-Blind Method
Hemodynamics
Maintenance
Pain
Injections

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Propofol 1% versus propofol 2% in children undergoing minor ENT surgery. / Pellégrini, Michel; Lysakowski, C.; Dumont, L.; Borgeat, A.; Tassonyi, E.

In: British Journal of Anaesthesia, Vol. 90, No. 3, 01.03.2003, p. 375-377.

Research output: Article

Pellégrini, Michel ; Lysakowski, C. ; Dumont, L. ; Borgeat, A. ; Tassonyi, E. / Propofol 1% versus propofol 2% in children undergoing minor ENT surgery. In: British Journal of Anaesthesia. 2003 ; Vol. 90, No. 3. pp. 375-377.
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