Primary rhabdoid cancer of the ileum: A case report and review of the literature

L. Tóth, Z. Nemes, Szabolcs Gomba, László Asztalos, Csaba Molnár, C. András, Z. Szentirmay, P. Molnár

Research output: Article

12 Citations (Scopus)

Abstract

Since the first publication of a rhabdoid cancer, described as an infrequent variant of Wilms' tumor, several cases of extrarenal rhabdoid tumor have been reported in the literature. Here, we report on a primary rhabdoid cancer of the small intestine, and give a review of the data available in the literature. An 81-year-old male patient was admitted to the Department of Internal Medicine with subileus and bloody stools. While gastroscopy and colonoscopy failed to identify a neoplastic disease, abdominal US and CT raised the suspicion of a malignancy involving the descending colon. Ileus-mandated laparotomy disclosed an obstructive tumor of the ileum. This segment was resected, followed by several relapses, and the patient died after a 7-month-period of non-relenting deterioration. Histological work-up of the numerous biopsies disclosed a cellular, solid, necrotic, hemorrhagic, and invasive tumor. The cancer cells were round-to-polygonal, and scattered bizarre pleomorphic cells with prominent nucleoli were common. The overall appearance of the neoplasm was highly similar in every specimen. The immunohistochemical phenotype of the malignant cells indicated rhabdoid characteristics. A thorough search of the literature revealed additional 22 cases of primary rhabdoid GI cancers. This report aims to call the pathologist's attention to the differential diagnostic importance of this entity.

Original languageEnglish
Pages (from-to)110-115
Number of pages6
JournalPathology Research and Practice
Volume206
Issue number2
DOIs
Publication statusPublished - febr. 15 2010

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Ileum
Neoplasms
Rhabdoid Tumor
Intestinal Neoplasms
Descending Colon
Gastroscopy
Wilms Tumor
Ileus
Colonoscopy
Internal Medicine
Laparotomy
Small Intestine
Publications
Phenotype
Biopsy
Recurrence

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Cell Biology

Cite this

Primary rhabdoid cancer of the ileum : A case report and review of the literature. / Tóth, L.; Nemes, Z.; Gomba, Szabolcs; Asztalos, László; Molnár, Csaba; András, C.; Szentirmay, Z.; Molnár, P.

In: Pathology Research and Practice, Vol. 206, No. 2, 15.02.2010, p. 110-115.

Research output: Article

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