Presence of PACAP and VIP in embryonic chicken brain

Rita Jozsa, Tibor Hollosy, Jozsef Nemeth, Andrea Tamás, Andrea Lubics, Balazs Jakab, Andras Olah, Akira Arimura, Dora Reglödi

Research output: Article

4 Citations (Scopus)


The aim of the present article was to investigate the occurrence and temporary changes of pituitary adenylate cyclase-activating polypeptide (PACAP)-38 and vasoactive intestinal peptide (VIP) in various brain areas of chicken embryos by means of radioimmunoassay. The highest concentrations of PACAP-38 were measured in the brain stem followed by the hypothalamus, cerebellum, and telencephalon. PACAP-38 levels were significantly higher than those of VIP in all examined brain areas. The levels of both PACAP-38 and VIP showed a tendency to decrease until hatching during embryonic development of the chicken.

Original languageEnglish
Pages (from-to)348-353
Number of pages6
JournalAnnals of the New York Academy of Sciences
Publication statusPublished - júl. 2006

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

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