The authors report on a prospective, randomized, controlled trial evaluating the efficacy of perioperative ampicillin/sulbactam prophylaxis in elective caesarean section. A total number of 104 pregnant patients were enrolled into the study. 60 of these patients were given three equal doses of 1.5 g ampicillin/sulbactam intravenously, while 44 served as controls. Perioperative antibiotic prophylaxis resulted in a significant decrease in the incidence of postoperative febrile morbidity (p<0.05), postoperative wound infections (p<0.002), postoperative endometritis with a temperature above 38 °C, and number of patients receiving additional antibiotic treatment (p<0.01). The use of ampicillin/sulbactam was not accompanied by any side effect. The authors conclude that perioperative ampicillin/sulbactam prophylaxis in cases of elective caesarean sections is a safe and effective method for preventing postoperative infectious morbidity.
|Number of pages||4|
|Journal||Magyar Noorvosok Lapja|
|Publication status||Published - jún. 17 1994|
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynaecology