Postoperative infectious morbidity after perioperative ampicillin/sulbactam prophylaxis in women undergoing elective caesarean section

I. Sziller, J. Karovits, F. Erdosi, A. Beke, G. Oszoli

Research output: Article

2 Citations (Scopus)

Abstract

The authors report on a prospective, randomized, controlled trial evaluating the efficacy of perioperative ampicillin/sulbactam prophylaxis in elective caesarean section. A total number of 104 pregnant patients were enrolled into the study. 60 of these patients were given three equal doses of 1.5 g ampicillin/sulbactam intravenously, while 44 served as controls. Perioperative antibiotic prophylaxis resulted in a significant decrease in the incidence of postoperative febrile morbidity (p<0.05), postoperative wound infections (p<0.002), postoperative endometritis with a temperature above 38 °C, and number of patients receiving additional antibiotic treatment (p<0.01). The use of ampicillin/sulbactam was not accompanied by any side effect. The authors conclude that perioperative ampicillin/sulbactam prophylaxis in cases of elective caesarean sections is a safe and effective method for preventing postoperative infectious morbidity.

Original languageEnglish
Pages (from-to)101-104
Number of pages4
JournalMagyar Noorvosok Lapja
Volume57
Issue number2
Publication statusPublished - jún. 17 1994

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynaecology

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