Possible morphological correlates of capsaicin desensitization

Elizabeth Király, G. Jancsó, M. Hajós

Research output: Article

20 Citations (Scopus)

Abstract

The changes in the fine structure of axonal profiles of the guinea-pig ureter were examined after exposure to capsaicin in vitro. In the ureters exposed to capsaicin (1-10 μM), about 60%, of all axonal profiles exhibited conspicous ultrastructural impairment. It is suggested that these alterations might interfere with the release of peptides from these particular nerve endings and therefore contribute significantly to the mechanisms of capsaicin desentization.

Original languageEnglish
Pages (from-to)279-282
Number of pages4
JournalBrain Research
Volume540
Issue number1-2
DOIs
Publication statusPublished - febr. 1 1991

Fingerprint

Capsaicin
Ureter
Nerve Endings
Guinea Pigs
Peptides

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Possible morphological correlates of capsaicin desensitization. / Király, Elizabeth; Jancsó, G.; Hajós, M.

In: Brain Research, Vol. 540, No. 1-2, 01.02.1991, p. 279-282.

Research output: Article

Király, Elizabeth ; Jancsó, G. ; Hajós, M. / Possible morphological correlates of capsaicin desensitization. In: Brain Research. 1991 ; Vol. 540, No. 1-2. pp. 279-282.
@article{05f1c5ab211c4d409f99e6a69a6289f6,
title = "Possible morphological correlates of capsaicin desensitization",
abstract = "The changes in the fine structure of axonal profiles of the guinea-pig ureter were examined after exposure to capsaicin in vitro. In the ureters exposed to capsaicin (1-10 μM), about 60{\%}, of all axonal profiles exhibited conspicous ultrastructural impairment. It is suggested that these alterations might interfere with the release of peptides from these particular nerve endings and therefore contribute significantly to the mechanisms of capsaicin desentization.",
keywords = "Capsaicin desentization, Capsaicin-sensitive nerve fiber, Fine structure, Guinea pig, In vitro, Ureter",
author = "Elizabeth Kir{\'a}ly and G. Jancs{\'o} and M. Haj{\'o}s",
year = "1991",
month = "2",
day = "1",
doi = "10.1016/0006-8993(91)90518-Z",
language = "English",
volume = "540",
pages = "279--282",
journal = "Brain Research",
issn = "0006-8993",
publisher = "Elsevier",
number = "1-2",

}

TY - JOUR

T1 - Possible morphological correlates of capsaicin desensitization

AU - Király, Elizabeth

AU - Jancsó, G.

AU - Hajós, M.

PY - 1991/2/1

Y1 - 1991/2/1

N2 - The changes in the fine structure of axonal profiles of the guinea-pig ureter were examined after exposure to capsaicin in vitro. In the ureters exposed to capsaicin (1-10 μM), about 60%, of all axonal profiles exhibited conspicous ultrastructural impairment. It is suggested that these alterations might interfere with the release of peptides from these particular nerve endings and therefore contribute significantly to the mechanisms of capsaicin desentization.

AB - The changes in the fine structure of axonal profiles of the guinea-pig ureter were examined after exposure to capsaicin in vitro. In the ureters exposed to capsaicin (1-10 μM), about 60%, of all axonal profiles exhibited conspicous ultrastructural impairment. It is suggested that these alterations might interfere with the release of peptides from these particular nerve endings and therefore contribute significantly to the mechanisms of capsaicin desentization.

KW - Capsaicin desentization

KW - Capsaicin-sensitive nerve fiber

KW - Fine structure

KW - Guinea pig

KW - In vitro

KW - Ureter

UR - http://www.scopus.com/inward/record.url?scp=0026082898&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026082898&partnerID=8YFLogxK

U2 - 10.1016/0006-8993(91)90518-Z

DO - 10.1016/0006-8993(91)90518-Z

M3 - Article

C2 - 2054619

AN - SCOPUS:0026082898

VL - 540

SP - 279

EP - 282

JO - Brain Research

JF - Brain Research

SN - 0006-8993

IS - 1-2

ER -