Personality and cardiovascular risk: Association between hypertension and affective temperaments-A cross-sectional observational study in primary care settings

Ajandek Eory, Xenia Gonda, Zsolt Lang, Peter Torzsa, Janos Kalman, Laszlo Kalabay, Zoltan Rihmer

Research output: Article

17 Citations (Scopus)

Abstract

Background: Affective temperaments can be considered the subclinical manifestations of affective disorders, which have a bidirectional relationship with cardiovascular diseases. Objectives: Aim of this study was to assess the role of affective temperaments in primary hypertension, which is the leading risk factor of cardiovascular morbidity and mortality. Methods: In total, 251 consecutive patients, including 179 patients being treated for primary hypertension with anti-hypertensives, with chronic disorders without diagnosed depression were enrolled in a primary care setting. Patients completed the Temperament Evaluation of Memphis, Pisa, Paris and San Diego Autoquestionnaire (TEMPS-A). Lifestyle-related risk factors, chronic diseases including cardiovascular complications were also recorded. Logistic regression analysis was used to determine the relationship of affective temperaments and lifestyle-related risk factors on hypertension. Results: Dominant cyclothymic temperament-with instability and rapid mood swings as main characteristics-had a significant association with hypertension (P = 0.006) even after the adjustment of correlation for known risk factors such as age, diabetes mellitus and obesity (OR: 11.88, 95%CI: 1.27-111.17). This association remained significant after controlling for the family wise error rate. The obtained adjusted P value was 0.024 at a 0.05 error rate. Conclusion: Results indicate that dominant cyclothymic affective temperament may be an additional risk factor in cardiovascular morbidity, and it may be worthy of further assessment to identify patients at risk and formulate a more individualized treatment approach.

Original languageEnglish
Pages (from-to)247-252
Number of pages6
JournalEuropean Journal of General Practice
Volume20
Issue number4
DOIs
Publication statusPublished - dec. 1 2014

ASJC Scopus subject areas

  • Family Practice

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