Peripheral opioid receptors mediating antinociception in inflammation: Localization on primary afferent neurons

C. Stein, A. H.S. Hassan, L. Bartho, C. Gramsch, A. Herz

Research output: Conference contribution

Abstract

Increased amounts of immunoreactive opioid receptors are visualized on cutaneous nerves in inflamed tissue. The enhanced antinociceptive effect of morphine in inflammation, previously shown to be due to a recruitment of peripheral opioid receptors, is abolished by capsaicin, suggesting that these receptors are located on primary afferent neurons.

Original languageEnglish
Title of host publicationNew leads in opioid research
Subtitle of host publicationproceedings of the International Narcotics Research Conference. ICS914
EditorsJ.M. Van Ree, A.H. Mulder, V.M. Wiegant, T.B. Van Wimersma Greidanus, J.M. Van Ree, A.H. Mulder, V.M. Wiegant, T.B. Van Wimersma Greidanus
PublisherElsevier Science Publishers B.V.
Number of pages1
ISBN (Print)044481213X
Publication statusPublished - jan. 1 1990
EventThe International Narcotics Research Conference -
Duration: júl. 8 1989júl. 13 1989

Publication series

NameNew leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914

Other

OtherThe International Narcotics Research Conference
Period7/8/897/13/89

ASJC Scopus subject areas

  • Medicine(all)

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    Stein, C., Hassan, A. H. S., Bartho, L., Gramsch, C., & Herz, A. (1990). Peripheral opioid receptors mediating antinociception in inflammation: Localization on primary afferent neurons. In J. M. Van Ree, A. H. Mulder, V. M. Wiegant, T. B. Van Wimersma Greidanus, J. M. Van Ree, A. H. Mulder, V. M. Wiegant, & T. B. Van Wimersma Greidanus (Eds.), New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914 (New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914). Elsevier Science Publishers B.V..