Parkinsonian symptoms with lithium, lithium-neuroleptic, and lithium-antidepressant treatment

Andrés Perényi, Zoltán Rihmer, Csaba M. Bánki

Research output: Article

14 Citations (Scopus)


Eighty-one patients treated for at least 3 months with lithium were examined for the presence of parkinsonian symptoms. Twenty-four patients were receiving treatment with lithium alone, 30 with lithium and 1 or more neuroleptics, and 27 with lithium and antidepressant. Twenty-four of the patients were found to be free from parkinsonian symptoms. Severe rigidity was not found. Two patients receiving neuroleptic with lithium and 6 on lithium-antidepressant combinations exhibited severe tremor. Neuroleptics administered concomitantly with lithium did not aggravate parkinsonian symptoms. The combination of lithium and an antidepressant significantly increased tremor in comparison to lithium alone.

Original languageEnglish
Pages (from-to)171-177
Number of pages7
JournalJournal of affective disorders
Issue number2
Publication statusPublished - máj. 1983

ASJC Scopus subject areas

  • Clinical Psychology
  • Psychiatry and Mental health

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