Two‐dimensional chemical shift correlation experiments (COSY and DEPT) may be applied to the detection of small spin‐spin couplings. To increase the sensitivity of these techniques, careful optimization of the experimental parameters is required. Equations applicable to AX spin systems are given for the optimal choice of delay periods in the pulse sequences. Practical applications have been demonstrated for oligosaccharide sequencing.
ASJC Scopus subject areas
- Materials Science(all)