On the acute hepatotoxicity of inhaled vinyl chloride

E. Tátrai, G. Ungvary

Research output: Article

Abstract

Acute toxicity of vinyl chloride exposure was studied by morphological methods in three species (mouse, rat, rabbit). In rats and rabbits exposure to 1500 ppm of vynil chloride for 24 hours did not cause pathological changes. In mice shorter inhalation (4 to 8 hours) resulted in circulatory changes, while longer exposure (12 and 24 hours) caused vasomotor paralysis followed by characteristic shock; subsequent alterations could be seen in the liver and lungs. The acute hepatotoxicity of vinyl chloride could not be proved.

Original languageEnglish
Pages (from-to)221-226
Number of pages6
JournalActa Morphologica Academiae Scientiarum Hungaricae
Volume29
Issue number2-3
Publication statusPublished - 1981

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Vinyl Chloride
Rabbits
Paralysis
Inhalation
Chlorides
Shock
Lung
Liver

ASJC Scopus subject areas

  • Anatomy

Cite this

On the acute hepatotoxicity of inhaled vinyl chloride. / Tátrai, E.; Ungvary, G.

In: Acta Morphologica Academiae Scientiarum Hungaricae, Vol. 29, No. 2-3, 1981, p. 221-226.

Research output: Article

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