Substituted cyclopentanes or tetrahydrofurans bearing two vinyl groups have been investigated in cross-metathesis reactions to explore chemodiscrimination of the two olefin bonds. The syntheses consisted of ring opening of constrained unsaturated β-lactams or bicyclic β-amino acids, followed by cross-metathesis to test the chemodifferentiation of the divinyl-substituted azetidinones or β-amino esters in the presence of various ruthenium-based catalysts.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry