Occurrence of tubuloreticular inclusions in acute viral hepatitis

Zsuzsa Schaff, Káaroly Lapis, Sáandor Keresztury, Zoltáan Kolláath, Margit Héarics, Iváan Hollóas

Research output: Article

13 Citations (Scopus)


Light and electron microscopy were used to study the liver needle-biopsy material of 20 patients with acute viral hepatitis. According to clinical and serologic data, 5 cases proved to be acute viral hepatitis type A, 13 were type B, and 2 were type non-A/non-B. In 2 of the hepatitis type A, in 6 of the hepatitis type B, and in one of the type non-A/non-B cases, tubuloreticular inclusions (TRI) were found in the endoplasmic reticulum of the sinusoidal endothelial cells of the liver. These data support the possible presumption that the inclusions represent a characteristic reaction of the endoplasmic reticulum to different influences, as for example to viral infection, rather than to the virus itself.

Original languageEnglish
Pages (from-to)169-173
Number of pages5
JournalUltrastructural Pathology
Issue number2
Publication statusPublished - jan. 1 1982

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Structural Biology

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