Non-alcoholic fatty liver disease (NAFLD)--a novel common aspect of the metabolic syndrome.

Katerina Bogdanova, Hana Poczatkova, Lenka Uherkova, Dagmar Riegrova, Miroslav Rypka, J. Fehér, Giulio Marchesini, Jaroslav Vesely

Research output: Article

17 Citations (Scopus)

Abstract

Non-alcoholic fatty liver disease (NAFLD) is emerging as one of the most common liver disorders claiming the urgent attention of both medical professionals and the public sphere because of the imminent epidemic of advanced liver injury that appendages epidemic of obesity. Recent research reveals simple triglyceride accumulation in hepatocytes (i.e., liver steatosis) frequently becoming complicated by inflammation (i.e., non-alcoholic steatohepatitis, or NASH) that may progress into more advanced stages of the disease including cirrhosis or, eventually, hepatocellular carcinoma. The exact mechanisms of the progression of NAFLD into overt NASH and advanced disease stages are largely unknown. There is urgent need in terms of both intensive research pursuits and effective practical measures to deal with this common threat.

Original languageEnglish
Pages (from-to)101-104
Number of pages4
JournalBiomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
Volume150
Issue number1
Publication statusPublished - júl. 2006

Fingerprint

Fatty Liver
Liver
Research
Hepatocytes
Hepatocellular Carcinoma
Triglycerides
Fibrosis
Obesity
Inflammation
Wounds and Injuries
Non-alcoholic Fatty Liver Disease

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Non-alcoholic fatty liver disease (NAFLD)--a novel common aspect of the metabolic syndrome. / Bogdanova, Katerina; Poczatkova, Hana; Uherkova, Lenka; Riegrova, Dagmar; Rypka, Miroslav; Fehér, J.; Marchesini, Giulio; Vesely, Jaroslav.

In: Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia, Vol. 150, No. 1, 07.2006, p. 101-104.

Research output: Article

Bogdanova, K, Poczatkova, H, Uherkova, L, Riegrova, D, Rypka, M, Fehér, J, Marchesini, G & Vesely, J 2006, 'Non-alcoholic fatty liver disease (NAFLD)--a novel common aspect of the metabolic syndrome.', Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia, vol. 150, no. 1, pp. 101-104.
Bogdanova, Katerina ; Poczatkova, Hana ; Uherkova, Lenka ; Riegrova, Dagmar ; Rypka, Miroslav ; Fehér, J. ; Marchesini, Giulio ; Vesely, Jaroslav. / Non-alcoholic fatty liver disease (NAFLD)--a novel common aspect of the metabolic syndrome. In: Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia. 2006 ; Vol. 150, No. 1. pp. 101-104.
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