New types of α-amylase enzyme-inhibitory polysaccharides from d-glucal

Sándor Kéki, Gyula Batta, Ilona Bereczki, Zsolt Fejes, Lajos Nagy, Ágnes Zajácz, Lili Kandra, Imre Kiricsi, György Deák, Miklós Zsuga, Pál Herczegh

Research output: Article

3 Citations (Scopus)

Abstract

We describe the synthesis of new types of α-amylase enzyme-inhibitory polysaccharides obtained by polycondensation of 3,6-Di-O-acetyl-d-glucal followed by deacetylation. The structure of the resulting new polysaccharides containing unique 2,3-unsaturated hexopyranose repeating units were unambiguously determined by NMR and MALDI-TOF MS methods. The deacetylated polysaccharides proved to be a semicompetitive inhibitor of the human salivary amylase enzyme.

Original languageEnglish
Pages (from-to)136-140
Number of pages5
JournalCarbohydrate Polymers
Volume63
Issue number1
DOIs
Publication statusPublished - jan. 18 2006

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ASJC Scopus subject areas

  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry

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