New components from Silybum marianum L. fruits

A theory comes true - In memoriam of Professor Szabolcs Nyiredy (1950-2006)

S. Nyiredy, Zoltán Szucs, S. Antus, Zsuzsanna Samu

Research output: Article

5 Citations (Scopus)

Abstract

The fruits of Silybum marianum L. (milk thistle) has been used for the treatment of hepatic and biliary diseases since ancient times. As separation techniques improved several isomers of silybin-the first determined active compound of milk thistle-have been described. Moreover, a new variety, the white-flowered S. marianum was discovered which contains deoxy-derivatives of some of the flavanolignans found in the purple-flowered variety. Based on this observation Nyiredy presumed that the deoxy-derivatives of all known flavanolignans of the purple-flowered variety are present in the white-flowered one. To prove this prediction several separations have been developed by the use of "PRISMA" principle.

Original languageEnglish
JournalChromatographia
Volume68
Issue numberSUPPL. 1
DOIs
Publication statusPublished - okt. 2008

Fingerprint

Milk Thistle
Fruits
Fruit
Derivatives
Isomers
Milk
Liver

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Clinical Biochemistry
  • Organic Chemistry

Cite this

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abstract = "The fruits of Silybum marianum L. (milk thistle) has been used for the treatment of hepatic and biliary diseases since ancient times. As separation techniques improved several isomers of silybin-the first determined active compound of milk thistle-have been described. Moreover, a new variety, the white-flowered S. marianum was discovered which contains deoxy-derivatives of some of the flavanolignans found in the purple-flowered variety. Based on this observation Nyiredy presumed that the deoxy-derivatives of all known flavanolignans of the purple-flowered variety are present in the white-flowered one. To prove this prediction several separations have been developed by the use of {"}PRISMA{"} principle.",
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T1 - New components from Silybum marianum L. fruits

T2 - A theory comes true - In memoriam of Professor Szabolcs Nyiredy (1950-2006)

AU - Nyiredy, S.

AU - Szucs, Zoltán

AU - Antus, S.

AU - Samu, Zsuzsanna

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N2 - The fruits of Silybum marianum L. (milk thistle) has been used for the treatment of hepatic and biliary diseases since ancient times. As separation techniques improved several isomers of silybin-the first determined active compound of milk thistle-have been described. Moreover, a new variety, the white-flowered S. marianum was discovered which contains deoxy-derivatives of some of the flavanolignans found in the purple-flowered variety. Based on this observation Nyiredy presumed that the deoxy-derivatives of all known flavanolignans of the purple-flowered variety are present in the white-flowered one. To prove this prediction several separations have been developed by the use of "PRISMA" principle.

AB - The fruits of Silybum marianum L. (milk thistle) has been used for the treatment of hepatic and biliary diseases since ancient times. As separation techniques improved several isomers of silybin-the first determined active compound of milk thistle-have been described. Moreover, a new variety, the white-flowered S. marianum was discovered which contains deoxy-derivatives of some of the flavanolignans found in the purple-flowered variety. Based on this observation Nyiredy presumed that the deoxy-derivatives of all known flavanolignans of the purple-flowered variety are present in the white-flowered one. To prove this prediction several separations have been developed by the use of "PRISMA" principle.

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KW - Stereoselectivity

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