Neuromyelitis optica: újdonságok a Devic-betegség patogenezisében, diagnosztikájában és terápiájában

Péter Csécsei, Anita Trauninger, Sámuel Komoly, Zsolt Illés

Research output: Review article

3 Citations (Scopus)

Abstract

The identification of autoantibodies generated against the brain isoform water channel aquaporin4 in the sera of patients, changed the current diagnostic guidelines and concept of neuromyelitis optica (NMO). In a number of cases, clinical manifestation is spatially limited to myelitis or relapsing optic neuritis creating a diverse. NMO spectrum. Since prevention of relapses provides the only possibility to reduce permanent disability, early diagnosis and treatment is mandatory. In the present study, we discuss the potential role of neuroimaging and laboratory tests in differentiating the NMO spectrum from other diseases, as well as the diagnostic procedures and therapeutic options. We also present clinical cases, to provide examples of different clinical settings, diagnostic procedures and therapeutic decisions.

Translated title of the contributionNeuromyelitis optica spectrum: Novel concept of pathogenesis, diagnosis and treatment of Devic's disease
Original languageHungarian
Pages (from-to)2101-2109
Number of pages9
JournalOrvosi hetilap
Volume150
Issue number46
DOIs
Publication statusPublished - nov. 20 2009

Keywords

  • Aquaporin
  • Devic's disease
  • Neuromyelitis optica
  • Optic neuritis
  • Transverse myelitis

ASJC Scopus subject areas

  • Medicine(all)

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