Multidimensional Packed Capillary Coupled to Open Tubular Column Supercritical Fluid Chromatography Using a Valve-Switching Interface

Z. Juvancz, K. M. Payne, K. E. Markides, M. L. Lee

Research output: Article

16 Citations (Scopus)

Abstract

An on-line two-dimensional supercritical fluid chromatographic system (SFC/SFC) was constructed by utilizing a rotary valve Interface to provide independent flow control of the two dimensions. A cold trap was employed to refocus solutes from single or multiple fractional cuts, after being transferred to the second dimension. Improved performance, including time savings, was achieved with a packed capillary to open tubular column arrangement and two independently controlled pumps, compared to earlier reported single-pump open tubular column SFC/SFC and packed capillary column SFC/SFC systems. The packed capillary in the first dimension provided a rapid chemical class separation, while the open tubular column in the second dimension provided high resolution of closely related isomers.

Original languageEnglish
Pages (from-to)1384-1388
Number of pages5
JournalAnalytical Chemistry
Volume62
Issue number14
DOIs
Publication statusPublished - júl. 1990

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ASJC Scopus subject areas

  • Analytical Chemistry

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