A minor fizikális anomáliák gyakoribbak gyermekkori idiopátiás epilepsziában

Györgyi Csábi, Richárd Zsuppán, Sára Jeges, Tamás Tényi

Research output: Article

4 Citations (Scopus)

Abstract

Background: The prevalence of minor physical anomalies (prenatal errors of morphogenesis) was evaluated in patients with idiopathic epilepsy to get indirect data on the possible role of aberrant neurodevelopment in the etiology of the disease. Aim: Connecting to current opinions on a possible role of aberrant neurodevelopment in idiopathic epilepsy it seems important to introduce somatic trait marker research focusing on brain maldevelopment. Methods: A scale developed by Méhes (1985) was used to detect the presence or absence of 57 minor physical anomalies in 24 patients with idiopathic epilepsy and in 24 matched controls. Results: The mean value of all minor physical anomalies was significantly higher in the group of patients compared to controls. In case of 3 minor physical anomalies we could demonstrate statistically significant differences between children with epilepsy and the control sample. Two minor malformations (primitive shape of ears, double posterior hair whorl) and one phenogenetic variant (inner epicanthic folds) had a significantly higher frequency in patients compared to control individuals. Conclusion: The overrepresentation of minor physical anomalies in idiopathic epilepsy can strongly support the view that this disorder is related to pathological factors operating early in development.

Translated title of the contributionMinor physical anomalies are more common in children with idiopathic epilepsy
Original languageHungarian
Pages (from-to)115-120
Number of pages6
JournalNeuropsychopharmacologia Hungarica
Volume16
Issue number3
Publication statusPublished - szept. 1 2014

Keywords

  • Childhood epilepsy
  • Idiopathic epilepsy
  • Minor physical anomalies
  • Neurodevelopment
  • Somatic markers

ASJC Scopus subject areas

  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Clinical Neurology

Fingerprint Dive into the research topics of 'A minor fizikális anomáliák gyakoribbak gyermekkori idiopátiás epilepsziában'. Together they form a unique fingerprint.

  • Cite this